Metabolic Syndrome

Meta-analyses associate Mediterranean dietary patterns with improvements in several metabolic-syndrome components, including waist circumference, triglycerides, glucose, insulin resistance, and blood pressure.

• Recent review rated overall certainty very low because of heterogeneity.
• Individual components and populations vary substantially.
• Do not claim the Mediterranean diet cures or permanently reverses metabolic syndrome.
• Do not generalize improvement in individual biomarkers to reduction in long-term clinical events without separate evidence.

Not established by these records.

• Source 1: https://pubmed.ncbi.nlm.nih.gov/40565352/
• Source 2: https://pubmed.ncbi.nlm.nih.gov/21392646/

In a randomized trial of adults with high-normal blood pressure or grade 1 hypertension, DASH plus sodium restriction and Mediterranean diet plus sodium restriction reduced the odds of meeting metabolic-syndrome criteria compared with minimal intervention over three months. Several cardiometabolic markers also improved.

• Participants had high-normal blood pressure or grade 1 hypertension, so findings should not be generalized to all populations.
• Intervention lasted three months.
• Sodium restriction was part of both dietary interventions.
• Do not claim either dietary pattern permanently reverses metabolic syndrome.
• Do not infer long-term cardiovascular event reduction from this trial.

Not established.

• Source 1: https://pubmed.ncbi.nlm.nih.gov/38777087/